New Year’s Day Open Thread

Filed in National by on January 1, 2010

Well, it’s 2010. May it be better than 2009, probably one of the most miserable years I’ve ever experienced. Although, at least one good thing happened in 2009 – I joined the Delaware Liberal community. Thanks for giving me the opportunity, although I must be responsible for the lame-ification that anonone talks about. 🙁

Anyway, here’s an interesting science story to start out your year. Prions, proteins that contain no DNA, evolve. I’m not sure if this is comforting or extremely scary.

Jiali Li from the Scripps Institute in Florida has found that prions – the infectious proteins behind mad cow disease, CJD and kuru – are capable of Darwinian evolution, all without a single strand of DNA or its sister molecule RNA.

Prions are rogue version of a protein called PrP. Like all proteins, they are made up of chains of amino acids that fold into a complex three-dimensional structure. Prions are versions of PrP that have folded incorrectly and this misfolded form, called PrPSc, is social, evangelical and murderous. It converts normal prion proteins into a likeness of its abnormal self, and it rapidly gathers together in large clumps that damage and kill surrounding tissues.

Li has found that variation can creep into populations of initially identical prions. Their amino acid sequence stays the same but their already abnormal structures become increasingly twisted. These “mutant” forms have varying degrees of success in different environments. Some do well in brain tissue; others thrive in other types of cell. In each case, natural selection culls the least successful ones. The survivors pass on their structure to the “next generation”, by altering the folds of normal prion proteins.

This process follows the principles of Darwinian evolution, the same principles that shape the genetic material of viruses, bacteria and other living things. In DNA, mutations manifest as changes in the bases that line the famous double helix. In prions, mutations are essentially different styles of molecular origami. In both cases, they are selectively inherited and they can lead to adaptations such as drug resistance. In prions, it happens in the absence of any genetic material.

Prions are not considered living organisms, since they can’t reproduce on their own. I think this just shows that adaptation to one’s environment is a fundamental concept on Earth.

Conservative bloggers embarrass themselves again with the White House visitor’s list and with their ACORN obsession.

Far-right activists thought they’d hit the mother lode when they started going through the list of names. The Weekly Standard’s Michael Goldfarb proclaimed, “I tried to warn you, America. Rev. Wright and Bill Ayers!”

What conservatives didn’t realize is that, from time to time, different people have the same name. Yes, someone named William Ayers visited the White House this year, but not that William Ayers. Someone named Jeremiah Wright stopped by, but not that Jeremiah Wright. Michael Jordan and Michael Moore stopped by, but not the ones you know. Conservatives got excited for nothing.

And this week, they did it again. A far-right site discovered that Bertha Lewis was in the White House, just days before an ACORN controversy became national news. The site realized the possibility that there could be more than one Bertha Lewis, but nevertheless felt confident that they’d stumbled upon an important White House/ACORN nexis. The item’s headline didn’t leave room for ambiguity: “White House Visitors Log: ACORN CEO Bertha Lewis In Obama Residence Week Before Sting Videos Launched.”

It turns out it was just some woman named Bertha Lewis (she even had a different middle initial) that had visited the White House. You would think that after having been wrong last time they would have tried something like fact-checking this time. Fact-checking is for suckers!

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Opinionated chemist, troublemaker, blogger on national and Delaware politics.

Comments (12)

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  1. nemski says:

    Hmm, I find it odd that Ed Yong wrote, “Darwinian evolution” instead of just plain-old “evolution”. I mean I haven’t heard anyone say, “Newtonian gravity” or “Einsteinian(?) relativity”.

  2. That’s a good question nemski. You should comment on Ed Yong’s site and ask him.

    I figure he meant evolution as Darwin saw it, before DNA was known. This evolution does not depend on the transfer of genetic material, which is what makes fascinating.

  3. just kiddin says:

    2010! The Decade of FEAR!

  4. nemski says:

    just kiddin must have been asleep between 2001 and 2008.

  5. Lizard says:

    Judge dismisses all charges in Blackwater shooting

    By Del Quentin Wilber Washington Post Staff Writer
    Thursday, December 31, 2009; 4:15 PM

    A federal judge on Thursday threw out charges against five Blackwater Worldwide security guards accused of killing 14 people in a 2007 shooting in downtown Baghdad.

    In a 90-page opinion, U.S. District Judge Ricardo M. Urbina ruled that the government violated the guards’ rights by using their immunized statements to help the investigation. The ruling comes after a lengthy set of hearings that examined whether federal prosecutors and agents improperly used such statements that the guards gave to State Department investigators following the shooting on Sept. 16, 2007.

  6. just kiddin says:

    Nemski: The decade of fear began in 2000, the change president is extending it.

    Lizard: was just about to post that info. The reaction from the Iraqis must be stated.

    Iraqi Human Rights Minister said, “There was so much evidence gathering to prove Blackwater was guilty, we are astonished how any Judge could rule this way”. General Ray Odierno stated, “this ruling would create problems for the other security firms operating in Iraq. (How bout our soldiers still stuck in the quagmire). I could give a damn about “private murdering security firms, who have immunity from proscection) thank you George Bush.

    BBC reports: A secret army investigation unit in England, has been accused of widespread abuse of Iraqi prisoners by British soldiers. So it wasnt just americans torturning, but the Brits too? Well at least the Brits are investigating the actions of their soldiers.

    Afganis reporting, US soldiers entered private home and slaughtered seven children! Some of the children had been handcuffed before they were shot. How to influence friends huh!

    You won’t hear this on corporate media. “The false flaggers forget a blasting cap is required to detonate PETN and other plastic explosives. Sure it will burn, (its used with water to heat up can food), but a blasting cap was missing from the Christmas Day Underwear guy? Where is the guy who filmed the entire flight, why have’nt we heard why he was filming, what happened to him and his film? Why would the Captain of the plane or the Stewards permit someone to “film passengers on an overseas flight”, without asking why, and what for? No privacy issue there?

  7. nemski says:

    Oh, please, girlfriend.

  8. cassandra_m says:

    TSA withdraws its subpoenas against a blogger.

    Subpoenas that never should have been issued in the first place. But I’m sure our resident bedwetters out there would have sent this blogger to Gitmo too.

  9. Miscreant says:

    “I mean I haven’t heard anyone say, “Newtonian gravity” or “Einsteinian(?) relativity”.”

    Yep… About as extraneous as ‘Donvitian Mangoes”.

  10. anon says:

    link link link link link link link link link.

    why is that concept so hard for the scaly one to grasp?

  11. Miscreant says:

    “Subpoenas that never should have been issued in the first place.”

    Agreed. The TSA and the administration has far more important problems to resolve than tromping on some bloggers.

  12. I wish you a better year in every respect but politically.